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Chris Lupo is at the forefront of innovation and leadership in both the financial and healthcare sectors. He is the head of AFO, a multi-family office in Greenville, SC and Owner and Co-Manager of InvestSouth, an alternative investment platform for his family clients. Under his leadership, these companies support his clients’ planning, administrative, operational and investment objectives.

Chris has over fifteen years of experience with healthcare operating companies. His journey began in 2008 when he began representing one of the owners of HMR Advantage Health System. He was intricately involved in their sale of twenty-one nursing homes with a related hospice, rehab company and institutional pharmacy to a private equity-backed operator in 2010. The owners of HMR Advantage retained HMR Veteran Services where Chris has been a longtime advisor and in 2024 became a member of the Board of Directors.

In 2013, Chris advised Heritage Healthcare, a large regional contract therapy provider in a merger to form HealthPRO-Heritage which has become a nationwide $500MM+ revenue healthcare company. He subsequently served on the HealthPro-Heritage Board from 2013 to 2015 when the company completed its first private equity recap. In 2018, InvestSouth acquired Interim Healthcare of the Upstate, a homehealth, hospice and personal care provider in South Carolina where Chris serves as a board member and a lead operating partner.

Chris Lupo

Director of Operations, HMRx

After a post-college stint at the Heritage Foundation in Washington, DC, Chris honed his skills on the executive team of another local rapidly growing multi-site service business. The company was acquired as the initial platform for an international company entering the space. Chris went on to serve as an M&A manager for the buyer, sourcing and closing five acquisitions over the following eighteen months. Thereafter, from 2001-2007, he helped lead private investments in a single-family office in Greenville, SC.

Chris earned a degree in economics with a concentration in mathematics from Wofford College. He lives in Greenville, SC, with his wife, Alison. They have twin daughters in college.